Resident Evil 9 Requiem: All Safe Codes, Locations, Rewards, and Insanity Mode Combinations
In Resident Evil 9 Requiem, safes are more than optional loot containers — they are progression accelerators. Unlocking every safe yields valuable resources, exclusive upgrades, and the No Safe Is Safe trophy/achievement. We present every safe code, precise rotation direction, exact location, and complete reward breakdown across both Standard and Insanity modes.
This definitive guide covers:
- All Rhodes Hill Care Center safe codes
- All ARK Laboratory safe combinations
- Every Insanity mode code
- Exact rotation instructions
- Reward optimization strategy
Rhodes Hill Care Center – All Safe Codes and Locations
There are four safes located inside the Rhodes Hill Care Center section of Resident Evil 9 Requiem. Three require combinations; one is already open.
Bar & Lounge Safe Code (First Safe in RE9 Requiem)
Location: Bar & Lounge, Rhodes Hill Care Center
Availability: Early game
Combination:
< 10 > 80 < 30Rotation Guide:
- Turn left (clockwise) to 10
- Turn right (counterclockwise) to 80
- Turn left (clockwise) to 30
- Press Check
Rewards:
- 3× Antique Coins
- Grace’s S&S M232 pistol (nearby in the room)
These Antique Coins allow immediate Parlor upgrades, giving early survivability advantages.
Examination Room Safe Code
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- Examination Room Safe Code
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- Examination Room Safe Code
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- Examination Room Safe Code
Location: Examination Room
Availability: Shortly after Bar & Lounge
Combination:
> 30 < 10 > 50Rotation Guide:
- Turn right (counterclockwise) to 30
- Turn left (clockwise) to 10
- Turn right (counterclockwise) to 50
Rewards:
- 3× Antique Coins
With both early safes opened, players secure 6 Antique Coins — sufficient for critical early-game upgrades.
Waiting Room Safe (Already Open)
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- Waiting Room Safe (Already Open)
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- Waiting Room Safe (Already Open)
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- Waiting Room Safe (Already Open)
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- Waiting Room Safe (Already Open)
Location: Behind desk in Waiting Room
Status:
- Already open
- No combination required
Rewards:
- 2× Antique Coins
Although accessible immediately, this safe does not require solving.
Basement Furnace Forklift Room Safe Code
Location: Basement Furnace side room (after using Joint Plug)
Combination:
> 60 < 40 > 80Rotation Guide:
- Turn right (counterclockwise) to 60
- Turn left (clockwise) to 40
- Turn right (counterclockwise) to 80
Rewards:
- Raccoon Roundup Map (Rhodes Hill)
- 10× Handgun Ammo
The Raccoon Roundup Map marks every Mr. Raccoon statue in the Care Center, streamlining completion objectives for future runs.
ARK Laboratory – All Safe Codes and Locations
Two safes appear in the late-game ARK facility section.
ARK Sterilization Chamber Safe Code
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- ARK Sterilization Chamber Safe Code
Location: Rear of Sterilization Chamber
Code Source: Bioweapon Repository 05
Combination:
> 10 < 90 > 20Rotation Guide:
- Turn right (counterclockwise) to 10
- Turn left (clockwise) to 90
- Turn right (counterclockwise) to 20
Rewards:
- Med Injector
- 15× Handgun Ammo
- Molotov Cocktail
These resources are crucial due to the Licker-heavy encounter density in this area.
ARK Monitor Control Room Safe Code
Location: Adjacent to ARK Lobby (two-orb door area)
Code Source: Bioweapon Repository 05 container
Combination:
< 50 > 60 < 80Rotation Guide:
- Turn left (clockwise) to 50
- Turn right (counterclockwise) to 60
- Turn left (clockwise) to 80
Rewards:
- Med Injector
- Bottle of Acid
- Empty Bottle
These materials expand crafting flexibility during the final chapters.
Insanity Mode Safe Codes – Complete List
In Insanity Mode:
- Safe locations remain identical
- File placements remain identical
- Combinations change
Below are every Insanity difficulty combination:
| Safe Location | Insanity Code |
|---|---|
| Bar & Lounge | >20 <50 >30 |
| Examination Room | <50 >30 <90 |
| Waiting Room | Already open (empty) |
| Basement Furnace | <70 >50 <20 |
| Sterilization Chamber | <80 >50 <0 |
| Monitor Control Room | >20 <0 >70 |
Precise rotation direction remains mandatory.
Safe Unlock Flow Overview
Total Rewards Summary
Opening all Standard mode safes provides:
- 8× Antique Coins
- 25× Handgun Ammo
- 2× Med Injectors
- 1× Molotov Cocktail
- 1× Bottle of Acid
- 1× Empty Bottle
- 1× Raccoon Roundup Map
This inventory significantly enhances survivability, crafting options, and collectible tracking efficiency.
Precision Rotation Reminder
Every combination requires:
- Correct direction
- Exact stopping number
- Sequential input without interruption
Incorrect rotation direction invalidates the sequence.
100% Completion Strategy
To ensure full completion:
- Unlock all four Rhodes Hill safes before leaving the Care Center
- Retrieve ARK combinations before engaging high-density enemy zones
- Complete all safes in one playthrough for the trophy
Safe mastery eliminates resource shortages and dramatically improves late-game survivability.
Final Reference: All Resident Evil 9 Requiem Safe Codes (Standard Mode)
- Bar & Lounge:
<10 >80 <30 - Examination Room:
>30 <10 >50 - Waiting Room: Open
- Basement Furnace:
>60 <40 >80 - Sterilization Chamber:
>10 <90 >20 - Monitor Control Room:
<50 >60 <80
Every safe code in Resident Evil 9 Requiem is now fully documented, optimized, and structured for fast in-game reference. Unlock them all to secure maximum efficiency and earn the No Safe Is Safe achievement.
